More than just weight-loss. The health benefits of Semaglutide.
Oct 2, 2024
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#Semaglutide/#Ozempic and #Tirzepatide/#Mounjaro are FDA-approved medications that have had a tremendous impact on the health and wellness of more than 15 million US adults. Its news and social media coverage has been quite remarkable compared to any other medications of its kind, and for good reason. They were created for the treatment of Type 2 diabetes, but it was quickly learned that it has many other health benefits that spread like wildfire.
How does Semaglutide and Tirzepatide work?
They are both in a class of drugs called GLP-1 receptor agonists that copy the effects of a natural hormone called glucagon-like peptide-1 (GLP-1). They trigger the pancreas to produce insulin which reducing the hunger hormone ghrelin. This decreases appetite and slows down the rate of stomach emptying so patients find themselves eating and snacking less throughout the day since they feel fuller for longer periods of time. The end result is the lowering of blood sugar levels and promotion of weight loss.
Increasing insulin
They stimulate the pancreas to release insulin, which helps move glucose from the blood into cells for energy. This helps maintain stable blood sugar levels.
Reducing glucagon
They reduce the amount of glucagon released by the pancreas, which helps prevent blood sugar levels from rising.
Slowing digestion
They slow down gastric emptying, which can help with blood sugar management and prevent patients from over eating.
Reducing appetite
They can help reduce hunger and food cravings, and increase feelings of fullness. This can lead to eating smaller portions and consuming fewer fatty foods.
Increasing energy expenditure
They can help increase energy expenditure and fat burning, which can lead to weight loss.
Improving lipid metabolism
They may help improve lipid metabolism, which can lead to changes in cholesterol and triglyceride levels.
Tirzepatide is a dual agonist that targets both the GLP-1 and glucagon receptors, while Semaglutide is a single GLP-1 receptor agonist. This means that Tirzepatide may be more effective in weight loss and word has spread.
While both drugs have similar mechanisms of action, there are some key differences such as dosage, side effects and cost to consider before selecting one over the other.
What are the Health Benefits?
Not only are #Semaglutide and #Tirzepatide effective at lowering diabetic patient’s A1c levels, it surprisingly helped them drop 10-15% of body fat. Many patients would benefit from this type of weight loss. Studies have shown the reduction of risks linked to cardiovascular episodes such as heart attack and stroke in overweight adults with known heart disease with or without diabetes by 20% (Cleveland Clinic, 2024).
Reduce risk of major cardiac events: a SELECT trial found that Semaglutide reduced the risk of major cardiac events by 20%. This includes a reduction in the risk of heart attacks by 28%, non-fatal strokes by 7%, and cardiovascular-related deaths by 15%.
Reduce risk of heart failure
Reduce inflammation which is the body's response to injury, infection, or certain medical conditions.
Improve kidney health which can help protect cardiovascular health.
Improve vasculature
Obesity specifically affects different aspects of women’s health. Women with obesity are more likely to have heart disease, diabetes, and breast cancer than women without obesity.
#Semaglutide and #Tirzepatide can help reduce visceral fat (stored fat deep within the abdomen, surrounding vital organs like the stomach, liver, and intestines) which can be difficult to lose through diet and exercise alone. The reduction of visceral fat will improve overall body composition. It's also known as "toxic" fat because it produces more harmful chemicals and hormones than subcutaneous fat (the fat that's stored just below the skin). Visceral fat can increase the risk of serious health problems, including: Diabetes, Pre-diabetes, Heart disease, and Colorectal cancer.
Do you have Type II Diabetes?
The American Diabetes Association says that most adults with diabetes should have an A1C level of less than 7% to be considered healthy. When added to metformin, Semaglutide can reduce A1C levels by 1.5 to 1.8 percentage points!
Mana Loa Health offers affordable, safe and effective Medical Weight Loss options to meet every patient's specific health needs!
GLP1s such as Semaglutide or Tirzepatide (Injection)
Mana Loa's Mega Burn (Vitamin/Supplement Injection)
Lipo-Burn Oral tablets and more are available!
Patient safety is Mana Loa Health's top priority. The information discussed on this blog is not intended to recommend the self management of health problems or wellness. It is not intended to endorse or recommend any particular type of medical treatment or advice. The information provided on this website is for informational purposes and not a substitute for professional medical advice, diagnosis, or treatment. If you have questions or concerns about your health, please talk to your healthcare provider. No information contained on this blog should be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider.
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